Cannabidiol Use for Fibromyalgia: Prevalence of Use and Perceptions of Effectiveness in a Large Online Survey.

Authors:
Kevin Boehnke, Joel Gagnier, Lynne Matallana & David Williams. The Journal of Pain, Vol 22, No 5 (May), 2021: pp556-66.

Cannabinoids and Fibromyalgia:
Two weeks ago, we learnt about the condition Clinical Endocannabinoid Deficiency (CECD), which is when a low functioning endocannabinoid system (ECS) manifests as disease. The three most common CECD diseases are migraine, fibromyalgia, and irritable bowel syndrome. All CECD conditions have been shown to respond positively to treatment with cannabis. This week, we’re going to look more closely at fibromyalgia.

Many people report using a variety of cannabinoids to treat fibromyalgia. As we saw when we looked at migraines, cannabis that includes both THC and CBD is the most popular preparation, but non-psychoactive products that only contain CBD may also be helpful.

As a modulator of the ECS, there is good reason to expect that CBD could be used to treat fibromyalgia, which is supported by the results of this study. Although this study didn’t investigate the dose or type of CBD being used, it is recommended that patients start low, track their symptoms, and increase their doses gradually if needed. Water soluble Fringe Mana or Henko CBD is rapidly absorbed and highly bioavailable, allowing for fast distribution of CBD throughout the body. More research is needed to better understand how CBD can be used to reduce symptoms of fibromyalgia, but its excellent safety profile makes it a great therapeutic candidate

Fringe Commentary:
As a modulator of the ECS, there is good reason to expect that CBD could be used to treat migraines. While there isn’t much research in this area, preliminary studies have been positive. At this point, the optimal dose is unclear, but it is recommended that patients start low, track their symptoms, and increase their doses gradually if needed. Water soluble Fringe Mana or Henko CBD is likely a better choice than oil-based CBD because its absorption is much more rapid, allowing faster distribution of CBD throughout the body. More research is needed to better understand how CBD could be used both to prevent and treat migraines, but its excellent safety profile makes it an great therapeutic candidate.

Links:
https://pubmed.ncbi.nlm.nih.gov/33400996/

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