Adult Immune Tincture

• Organic Turkey Tail Extract (Trametes versicolor, whole fruiting body): 500 mg
• Organic Reishi Extract (Ganoderma lucidum, whole fruiting body): 500 mg
• Organic Elderberry Extract (Sambucus nigra, fruit): 400 mg
• Organic Astragalus Extract (Astragalus membranaceus, root): 500 mg

Other ingredients: organic vegetable glycerin (flaxseed-derived), purified water, organic raspberry extract.

Turkey tail. The anchor mushroom. Its cell walls are built from beta-glucans, a pattern of sugar molecules that immune cells have dedicated receptors to recognize, a well-characterized interaction that helps immune cells get ready to do their job.†¹ Some turkey tail compounds also reach the gut largely undigested, where beneficial bacteria ferment them. In a randomized controlled trial in healthy adults, turkey tail shifted gut bacteria in ways consistent with a prebiotic effect.†² Since so much immune tissue lives in the gut, feeding those bacteria is another way to support immune function.†

Reishi. Reishi brings its own beta-glucans in a slightly different configuration. In a randomized controlled trial in healthy adults, reishi beta-glucan was studied for its effects on immune cells, including T cells and natural killer cells,†³ and an earlier controlled study in healthy adults looked at immune and antioxidant biomarkers.⁴ Reishi also carries a second group of compounds called triterpenes, which work through different signaling pathways. Triterpenes dissolve in alcohol, not water, which is why our extraction uses both. Much of the triterpene research so far comes from lab studies.

Astragalus root. Known as huang qi, it’s one of the most-used roots in traditional Chinese herbalism, recorded as an immune tonic for centuries. Its polysaccharides engage immune sensing through a different pathway than mushroom beta-glucans, so astragalus complements the mushrooms rather than duplicating them.† Full transparency: research on astragalus on its own in healthy adults is limited. Most of it comes from lab studies or multi-herb formulas, so its place here rests on that long traditional record plus mechanism research.

Elderberry. Used for generations across Europe and North America, especially in the cooler months. Its deep purple color comes from anthocyanins, antioxidant plant compounds.†⁵

Each ingredient was chosen to support the immune system from a different angle: beta-glucans for direct immune sensing, turkey tail for the gut-immune connection, reishi’s triterpenes and astragalus’s polysaccharides for separate signaling pathways, and elderberry for antioxidant support.†

Many mushroom supplements are made from mycelium, the root-like network that grows before a mushroom appears, cultivated on rice or oats. When those products are analyzed, they can turn out to be mostly the grain they were grown on. The fruiting body is the actual mushroom, where the active compounds concentrate.

Alcohol is a great extraction solvent and a terrible thing to taste. We use organic cane alcohol during extraction to capture the compounds water leaves behind, then remove it. The result is easy to take straight or in a drink, and a fit for anyone who avoids alcohol for personal, religious, dietary, or medication reasons.

Immune as a finished formula hasn’t been studied in its own clinical trial (yet). Each ingredient has its own research, though some of it is early or lab-based, and we call that out where it applies.

1. Saleh MH, Rashedi I, Keating A. (2017). Immunomodulatory properties of Coriolus versicolor: The role of polysaccharopeptide. Frontiers in Immunology, 8, 1087.
2. Pallav K, Dowd SE, Villafuerte J, et al. (2014). Effects of polysaccharopeptide from Trametes versicolor and amoxicillin on the gut microbiome of healthy volunteers: A randomized clinical trial. Gut Microbes, 5(4), 458–467.
3. Chiu HF, et al. (2023). Evaluation of immune modulation by β-1,3; 1,6 D-glucan derived from Ganoderma lucidum in healthy adult volunteers. Foods, 12(3), 659.
4. Wachtel-Galor S, Tomlinson B, Benzie IFF. (2004). Ganoderma lucidum, a Chinese medicinal mushroom: Biomarker responses in a controlled human supplementation study. British Journal of Nutrition, 91(2), 263–269.
5. Sidor A, Gramza-Michałowska A. (2015). Advanced research on the antioxidant and health benefit of elderberry (Sambucus nigra) in food: a review. Journal of Functional Foods, 18, 941–958.

Every day. Immune is designed for consistent daily use all year long, because steady beats sporadic. During busier or more stressful stretches, you can take 1 serving twice daily for up to 7 days, then go back to once daily.

No. We use organic cane alcohol during extraction to capture compounds water can’t, then remove it. The finished tincture is in a vegetable glycerin base.

Mildly sweet with a light raspberry flavor, and no alcohol burn. Take it straight from the dropper or stir it into coffee, tea, juice, water, or a smoothie.

Don’t use Immune if you’re pregnant or breastfeeding, have an autoimmune condition (such as multiple sclerosis, lupus, rheumatoid arthritis, psoriasis, Hashimoto’s, inflammatory bowel disease, or type 1 diabetes), take immunosuppressant medication, or have a mushroom or mold allergy. If you take any medication, have a health condition, or are scheduled for surgery, check with your healthcare provider before use.

Immune is for adults 18+. For kids ages 2–17, use Immune Kids, a separate formula with the same organic mushrooms and process, dosed by age.