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Red Light Therapy & Traumatic Brain Injury
What is Traumatic Brain Injury? Traumatic Brain Injury (TBI) occurs when the brain is damaged by an external force, like an impact, blast, or rapid acceleration/deceleration. Common causes of TBI include falls, sports injuries, vehicle accidents, and physical assaults. Damage from TBI’s can lead to long-lasting and even permanent impairment of brain function. TBI’s are common injuries in the US, with approximately 1.5 million Americans experiencing a TBI annually. TBI is considered an umbrella term that refers to any brain injury caused by an external source. TBI’s can be categorized by severity, ranging from mild to severe, and have unique characteristics: Mild TBI – Causes temporary confusion and headache. Moderate TBI – Causes prolonged confusion and cognitive impairment. Severe TBI – Causes significant cognitive deficits and long-term complications. TBI’s can also be categorized by timeframe, including both acute (short-term) and chronic (long-term) effects. The acute phase last from hours to weeks, while the chronic phase lasts from weeks to years, depending on the severity of the TBI. Two TBI-related terms that may be familiar to people are concussions and Chronic Traumatic Encephalopathy (CTE). Concussions are a type of mild TBI, and although symptoms usually resolve within days to weeks, they can still have long-term effects, especially with multiple incidents. One potential long-term consequence of repeated concussions is CTE, a progressive neurodegenerative disease believed to be caused by repeated head injuries, including multiple mild TBIs. Treatment for TBI varies greatly depending on the severity of the injury. In general, it involves stabilization, symptom management, and rehabilitation. The primary goal of treatment during the acute phase is to protect brain tissue and focuses on cognitive rest and addressing symptoms. In the chronic phase, the primary goal of treatment is to restore cognitive, motor, and emotional function. Emerging treatments such as Red Light Therapy may be beneficial in supporting the brain during both the acute and Shop Red Light Therapy Head Wrap How does TBI affect the Brain Before we consider how Red Light Therapy may be used to support brain health following TBI, let’s take a closer look at the three major pathological processes that occur in the brain during this type of injury. Neuroinflammation: TBI causes neuroinflammation, which occurs in the hours to days following the injury. Neuroinflammation is inflammation of the brain, which can be helpful in the short term but is harmful when prolonged, leading to chronic neurodegeneration. Excess neuroinflammation is linked to brain fog, mood disorders, and an increased risk of neurodegenerative diseases such as CTE. Oxidative stress: Following a TBI, the brain produces excessive amount of reactive oxygen species (ROS), which can lead to oxidative stress. Oxidative stress can overwhelm our antioxidant defenses and cause damage to cells in the brain, worsening brain injury. Impaired brain energy metabolism: TBI impairs brain energy metabolism, particularly the ability of the brain to use glucose, which leads to a metabolic crisis where neurons are deprived of energy. After an initial phase of excessive glucose use, there is a decrease in glucose availability that can last from days to weeks, which makes neurons more vulnerable to damage and impairs healing. These three factors interact and include many overlapping molecules. For example, both neuroinflammation and impaired brain energy metabolism can lead to an increase in ROS production, further worsening oxidative stress. Similarly, impaired energy metabolism exacerbates neuroinflammation. This creates a self-perpetuating cycle of damage, which is why TBI recovery can be slow and why some people experience persistent symptoms for weeks, months, or even years following the injury. How does Red Light Therapy support brain function? Red Light Therapy is a promising tool for supporting the brain during TBI because it targets all three foundational brain pathologies, including neuroinflammation, oxidative stress, and impaired brain energy metabolism. Using both red and near infrared light (especially near infrared, which has deeper penetration), Red Light Therapy delivers wavelengths that interact with light sensitive molecules inside brain cells. Here's how Red Light Therapy affects neuroinflammation, oxidative stress, and brain energy metabolism: Neuroinflammation: Red and near infrared light wavelengths have anti-inflammatory effects, and unlike anti-inflammatory medications (such as NSAID’s), do not cause side effects. Studies have found that light therapy affects levels of many molecules involved in inflammation, including ROS, reactive nitrogen species, and prostaglandins. Red and near infrared light therapy have specifically shown to reduce neuroinflammation. Oxidative stress: Light is absorbed in cells by molecules called chromophores, many of which are found inside the mitochondria. Mitochondria are involved in regulating the production the ROS that cause oxidative stress when present in high amounts. Light therapy has been shown to modulate oxidative stress and ROS production. Impaired brain energy metabolism: Through its impact on mitochondria, light also affects metabolism. In addition to regulating ROS production, mitochondria also make ATP, which is the energy currency of the cell, via a chain of molecules that includes cytochrome c oxidase. Cytochrome c oxidase is activated by both red and near infrared light, which increases ATP synthesis and provides more energy to brain cells. As well, there are additional effects of Red Light Therapy in the brain that may help to support healing from TBI. This includes increasing brain blood flow, supporting brain adaptability, and regulating neuron cell death. Collectively, there are many ways in which Red Light Therapy may be used therapeutically in TBI, and these have been explored in several clinical and pre-clinical studies of both acute and chronic TBI. Is there evidence to support the use of Red Light Therapy in TBI? Yes! Red Light Therapy has been investigated in several studies of TBI using a range of different experimental approaches. These studies can be broken down by timeframe into both acute and chronic TBI, as well as by study type, including clinical (using humans as subjects) and pre-clinical (using animals as subjects). Acute TBI The acute phase of TBI immediately follows the onset of injury. Unfortunately, this creates some challenge in coordinating and executing research studies, since it is difficult to recruit human subjects into a research study who have just experienced a head injury. As a result, most of the research in this TBI phase has been done using animals given a head injury in a controlled environment. In a 2023 systematic review of 17 animal studies that used Red Light Therapy immediately post-TBI, it was found that early light therapy intervention could improve neurological outcomes and reduce the size of trauma-associated brain lesions. Optimal results were associated with both red and near infrared light, initiation within 4 hours post-injury, and up to three daily treatments. One human study was included in the review of Red Light Therapy for acute TBI, which suggested safety and feasibility, but treatment efficacy could not be determined. Chronic TBI Many more human studies have explored the use of Red Light Therapy in the chronic phase of TBI, which occurs weeks to months after the initial trauma. In a 2024 review of 16 human studies, overall improvements in neuropsychological outcomes and increased cerebral blood flow following transcranial PBM were observed. Here are some highlights of the clinical research findings: How can I use Red Light Therapy in TBI? 2019 study of 12 military veterans with chronic TBI lasting more than 18 months – Following six weeks of application of both red and near infrared light to the head using LED lights, neuropsychological scores and brain blood flow were improved. 2020 case report of 23-year professional hockey player with a history of concussions, and symptoms of headaches, mild anxiety, and difficulty concentrating - Following 8 weeks of application of near infrared light to the head using LED lights, many positive findings were observed, including increased brain volume, improved brain connectivity, increased brain blood flow, and improved neuropsychological test scores. 2023 study of four retired professional football players with suspected CTE – Following application of near infrared light to the head using LED lights three times per week for six weeks, a wide range of improvements were noted, including improved sleep, reduced depression, decreased PTSD, and decreased pain. Analysis of brain function showed several improvements. Collectively, research looking at the use of Red Light Therapy to support healing from TBI has yielded positive outcomes, both subjective (such as improved mood and decreased pain), and objective (such as increased brain volume and blood flow). There is stronger support for the use of Red Light Therapy in chronic TBI, but pre-clinical evidence supports the potential for benefit during the acute phase of injury. TBI Recovery Managing TBI involves a combination of stabilization, symptom relief, and rehabilitation, each playing a crucial role in recovery. Red Light Therapy is a safe and effective tool that can support healing throughout all three stages. While it can be conveniently done at home using a Red Light Therapy device, professional supervision is recommended during the acute phase to ensure safe and effective application. When exploring the range of available options, here are four things to consider: Light wavelength – The wavelength of light determines its color, with red light in the range of 620-700nm and near infrared light in the range of 700-1100nm. Although near infrared has been used most often to support healing from TBI, some studies have also found benefit from red light. Light with wavelengths between 600 and 1300nm have been found to penetrate maximally into the brain. So, look for products that provide both RL and NIRL in combination. Light intensity - Light intensity refers to the amount of light being delivered by a device, also referred to as power density. Studies of Red Light Therapy and TBI have used a range of intensities, from 10-100mW/cm2, and there is no clear indication that a particular intensity must be used. Devices across a range of intensities may provide benefit, and consumers aren’t limited to a specific intensity range. Type of device - Your personal level of comfort with a device is important. If it isn’t easy to use, and if it doesn’t feel good on your body, you probably won’t use it consistently. Many consumers find the most convenient devices to use are wireless, with a rechargeable battery. It is also important to use a device that can be adjusted to fit snugly on the head. Think about your personal preferences and choose a device that fits your criteria. Light Source - Light therapy is administered using either laser or LED lights. While early light therapy research was done using lasers, LED lights have become much more popular over the last decade. For at home use, look for a device that uses LED lights as safe and affordable option. The next step after selecting a Red Light Therapy device is to determine the treatment protocol. During the acute phase of TBI, it is recommended to consult with your health care provider to get their professional guidance regarding the most appropriate protocol for your case. During the chronic phase of TBI, support from a health care professional is also recommended, but people may be more independent during this period. Based on available clinical research, 10-40 minute treatment sessions, 3 to 5 times a week, are recommended. Do not exceed more than one session every 24 hours. Conclusion Red Light Therapy is a safe, affordable, and highly effective tool for supporting at-home recovery from TBI. By targeting the three core drivers of brain injury—oxidative stress, impaired metabolism, and neuroinflammation—it offers a scientifically backed approach to healing. Research suggests benefits across all stages of TBI, from the critical early hours to years post-injury. When choosing a device, look for red and near-infrared LED technology that aligns with your needs for comfort and convenience, empowering you to take an active role in your recovery. Shop Red Light Therapy Head Wrap For more information about Fringe light products, go to: https://fringeheals.com/shop-all-products/
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Red Light Therapy vs Ice
Red Light Therapy vs Ice. If you were to take a sample of doctors and athletic trainers and ask them what therapy they recommend that people use for post-exercise muscle recovery, you are guaranteed to find that a majority will tell you to apply ice. Cryotherapy or icing has long been considered the gold standard for dealing with pretty much any kind of inflammatory process, including the muscle inflammation that occurs following strenuous exercise. Cryotherapy is a therapeutic technique that involves exposing the body or specific areas to extremely cold temperatures, typically using ice packs, cold water immersion, or specialized cryochambers. But research has now clearly shown that when you put icing head-to-head with Red Light Therapy – which uses red and/or near infrared light to influence biology - and look at which one works better to support exercise recovery, Red Light Therapy consistently comes out on top. In 2019, a scientific article was published that reviewed three clinical trials and two animal studies comparing cryotherapy to Red Light Therapy. Each human clinical trial administered both red and near infrared light, while the two animal studies used near infrared light only, and light or cryotherapy were applied following exercise. The outcome for each study was post-exercise muscle recovery. All five studies found that Red Light Therapy was superior to cryotherapy at improving outcomes related to exercise recovery. This included decreased delayed onset muscle soreness and reduced muscle inflammation. The research also showed that in contrast to Red Light Therapy, cryotherapy did nothing to prevent muscle damage from occurring following strenuous exercise, since markers of muscle damage like creatine kinase were only reduced with Red Light Therapy. The superiority of Red Light Therapy over cryotherapy makes perfect sense when you consider the mechanisms of how the two modalities work. In a nutshell, red light therapy stimulates mitochondria to produce energy and modulate oxidative stress, decreasing cellular markers of inflammation. Red Light Therapy also induces cellular changes like increasing the production of growth factors. This is how it can have effects such as decreasing inflammation and healing damaged muscle fibers, and how it can positively influence many aspects of exercise recovery. In contrast, cryotherapy constricts blood vessels and decreases blood flow, which leads to less edema formation (swelling). This might reduce inflammation and decrease pain, but it really does nothing on a cellular level to support healing. In fact, it’s been argued by some experts to do the opposite. Several criticisms of cryotherapy have been raised, including that it only provides temporary relief and does not promote long-term healing. The studies described in this analysis used light that was quite low in intensity. Light intensity refers to the amount of light being delivered by a device. It is also sometimes called irradiance, and it’s usually measured in units called mW/cm2. Red Light Therapy devices on the market vary widely in terms of their intensity. While it’s common to see marketing claims that high intensity products (at upwards of 100mw/cm2) are needed to reap the benefits of Red Light Therapy, this research (and a lot of other studies too), show that this is false. When it comes to using Red Light Therapy for post-exercise muscle recovery, research has clearly shown that more is not better. Instead of high intensity products, it’s best to use a device that delivers both red and near infrared light at a low to moderate intensity. Fringe Red Light Therapy products are great options for post-exercise support, delivering the optimal intensity of light at between 20 and 40mw/cm2. This is like the intensity of the sun. Fringe Red Light Therapy wraps even have the advantage of being portable and cordless, offering the flexibility of immediate use, including on the sideline! So, the next time you have a hard workout, reach for a Red Light Therapy device instead of ice to support muscle healing. And the advantages of Red Light Therapy over cryotherapy extend to healing for other conditions as well. Basically, you can use Red Light Therapy for anything that you would consider using ice for. By using Red Light Therapy instead, you’ll not only decrease pain and inflammation, but you’ll also activate cellular healing mechanisms that will help you to feel better faster. For more information about Fringe light products, go to: https://fringeheals.com/shop-all-products/
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Light Therapy and Vibration for Female Pelvic Health
One of our missions at Fringe is to create high quality, evidence-based light therapy products, and to make them readily accessible to consumers. Our goal is to help people heal from the conditions that commonly ail them – like arthritis, post-exercise muscle soreness, and eczema (just to name a few) - in the comfort of their own homes. Recently, we turned our attention to some of the more common conditions affecting women and those born female at birth specifically: disorders of the female pelvis. Disorders related to female pelvic health (including pelvic floor pain and dysfunction, urinary incontinence, sexual dysfunction, and vaginal infections) are incredibly common, affecting up to 50% of the population at some point in their lives. shop fringe pelvic wand Enter, the fringe pelvic wand In response, we made the Fringe Pelvic Wand - which combines light therapy with vibration, two well-established healing modalities - which may support recovery from these challenging issues. What is red light? Light therapy (also known as photobiomodulation) is the application of light with specific wavelengths to the body for the purposes of influencing biology. The most common form of light therapy uses red light, which is visible as the color red, and/or near infrared light, which is not visible but can be felt as heat. Blue light is also used in many light therapy products, mainly for its antimicrobial effects. Red, near infrared, and blue light are naturally produced by the sun, which gives off solar radiation. The term radiation describes energy that is transmitted in the form of waves or particles. The spectrum of light in our environment consists of both light we can see (visible light) and light that our eyes can’t perceive (invisible light). This is called the electromagnetic spectrum. The visible light spectrum is quite narrow, consisting of wavelengths that range from 400 to 700nm and span from violet to red in color. Blue and red light are part of this visible light spectrum, while near infrared light is not. Different colors of light have different depths of skin penetration, with red and near infrared light penetrating the deepest. While early research on light therapy used primarily lasers, more recent research has found that LED’s can also be used, which also have the advantage of applying light to a larger area of the body as well as an improved safety profile. The use of LED in red/near infrared/blue light therapy devices has also greatly reduced the cost of treatment, making it something that can be done in the comfort of one’s own home. Both laser and LED lights have been used in research and practice to support pelvic health. Light therapy delivers light at a measurable level of intensity, which can be generally classified as low, moderate, and high. The intensity of sunlight is between 20 and 40mW/cm2, which is described as the “sweet spot” between higher intensities, which can have harmful effects, and lower intensities, which will have no effect at all. This range is optimal for healing while minimizing adverse effects, and is the range used in the Fringe Pelvic Wand. How might light therapy support female pelvic health? Light therapy may have physiological effects related to female pelvic health, including: Tissue Rejuvenation Loss of connective tissue, such as collagen and elastin, in the female pelvis is commonly experienced by women as they age and can also occur because of childbirth and infections. Through its effects on mitochondria, light therapy (especially red and near infrared light) may increase cellular energy production and increase connective tissue production. Light therapy may also modulate the production of reactive oxygen species, causing a shift towards tissue rejuvenation rather than breakdown, and may support muscle strengthening. Reduced Inflammation & Pain Chronic pain is commonly associated with disorders of the pelvic floor, which may also be associated with pelvic inflammation. Light therapy (especially with red and near infrared light) may have powerful effects on inflammation. Studies have found that light therapy may affect levels of many molecules involved in inflammation, including reactive oxygen species, reactive nitrogen species, and prostaglandins. Increased Blood Flow A decrease in blood flow to tissues in the female pelvis, especially the vagina, occur with age. This loss of blood flow negatively affects tissues by reducing the supply of oxygen and nutrients and contributes to age associated changes such as vaginal atrophy. Light therapy (especially red and near infrared light) may increase blood flow in two ways. First, it may increase levels of nitric oxide through its effects on the mitochondria, which causes vasodilation. The dilation of blood vessels allows more blood to flow through. Second, it may increase angiogenesis, which is the synthesis of new blood vessels. A greater density of blood vessels may increase the delivery of blood to tissues. Effects on Microorganisms Infections with pathogenic microorganisms in the female pelvis are quite common, and include bacteria (such as chlamydia), fungi (such as candida), and viruses (such as HPV). The vagina also naturally hosts the vaginal microbiome, which has a balance of microorganisms. When imbalanced, susceptibility to infections and bacterial vaginosis is increased. Light may have effects on microorganisms, both pathogenic and non-pathogenic. Blue light may have powerful effects on pathogenic microbes that can infect the vagina, such as candida, while red light may have positive effects on the microbes that comprise the microbiome, including the vaginal microbiome. Some clinical conditions related to female pelvic health that may improve with light therapy include: Vaginal candidiasis Human papillomavirus and associated vaginitis and cervicitis Vulvovaginitis Chronic pelvic pain Urinary incontinence and sexual dysfunction Overactive bladder Interstitial cystitis/bladder pain syndrome Menopause Episiotomy recovery What is vibration therapy? Vibration therapy may have physiological effects related to female pelvic health, including: Tissue Rejuvenation Vibration therapy may have many effects on cells associated with the structural integrity of the female pelvic. Collagen in particular may respond to vibration therapy, especially at low magnitudes, and both collagen and muscle formation respond well to low magnitude vibration at between 8 and 10Hz. Increased Blood Flow Vibration therapy may increase blood flow, after as little as 10 minutes of therapy. Increasing blood flow helps to perfuse tissues with oxygen and nutrients and improve function and speed healing. Muscle Tone Regulation While proper functioning of the pelvic floor muscles is integral to bowel, bladder, and sexual health, in many women these muscles are weak. Others experience chronic hypertonicity in muscles of the pelvic floor, which is also suboptimal. Vibration therapy may regulate muscle tone in two ways. First, it may decrease spasticity in muscles that are overactive. Second, it may improve the potential to voluntarily contract muscles, such as those of the pelvic floor, which are poorly controlled in between 30 and 50% of women, and in this way activate and strengthen the muscle. Muscle tone regulation is accomplished by activating muscles via a spinal reflex and increasing blood flow. Decreased Pain Vibration therapy may reduce many different pain types, including neuropathic pain, low back pain, and muscle pain. This may happen via several mechanisms, such as regulating muscle tone and increasing blood flow. Some clinical conditions related to female pelvic health that may improve with vibration therapy include Urinary incontinence Pelvic floor dysfunction Vulvodynia (a pelvic pain condition) Pelvic pain penetration disorder Sexual dysfunction The Fringe Pelvic Wand The Fringe Pelvic Wand delivers three wavelengths of light via three modes: + Mode 1 - Deep Rejuvenation MODE ONE - red/near infrared light (630nm & 830nm): delivers both red (630nm) and near infrared (830nm) light to the pelvic tissues. This mode may help with pelvic pain and inflammation; bladder and muscle health; optimizing the vaginal microbiome; increasing the production of collagen and elastin; and improving blood flow and tissue health. Use Mode 1 for deep pelvic rejuvenation if you are NOT sensitive to light or heat. + Mode 2 - Antimicrobial MODE TWO - Blue Light (415 nm): delivers blue light (465nm) to the pelvic tissues. This mode may support the destruction of microbes including fungus and bacteria and healing from yeast infections and bacterial vaginosis. + Mode 3 - Rejuvenation MODE THREE - Red Light (630 nm): delivers only red (630nm) light to the pelvic tissues. This mode may help with pelvic pain and inflammation; bladder and muscle health; optimizing the vaginal microbiome; increasing the production of collagen and elastin; and improving blood flow and tissue health. Use Mode 3 for pelvic rejuvenation if you ARE sensitive to light or heat. The Fringe Pelvic Wand also delivers optional vibration, via four modes: + Mode 1 - 10hz (default mode) MODE ONE: provides very low frequency vibration which may help to support muscle relaxation and pain reduction. + Mode 2 - 50hz MODE TWO: provides low/moderate frequency vibration which may help to support muscle relaxation, reduce pain, and increase awareness of pelvic muscle function. Mode 2 can be combined with gentle pelvic floor exercises. + Mode 3 - 90hz MODE THREE: Provides moderate/high frequency vibration that increases awareness of pelvic muscle function and may help to support pelvic muscle contraction. Mode 3 can be combined with moderately active pelvic floor exercises. + Mode 4 - 120hz MODE FOUR: provides high frequency vibration that may help to support strengthening of pelvic muscles. Mode 4 can be combined with active pelvic floor exercises. Let's get started How to use the fringe pelvic wand Light & Vibration Therapy Safety The safety of light and vibration therapy has been demonstrated in thousands of research studies. However, there are some precautions to be aware of before you begin your therapeutic journey.Photosensitivity is the main contraindication to light therapy. If you are sensitive to light or are using medications that increase light sensitivity (see https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672668/ for a recent list), you may need to reduce treatment time, interval, and/or frequency, as well as reduce light intensity. Light & Vibration Therapy Safety Here are some other precautions to consider. Please don’t: Exceed the recommended treatment times and frequency. Use on open fresh wounds. Use in combination with lotions, balms or other topical products that contain heat producing ingredients. Use with a non-water based lubricant. If you’re pregnant, we recommend checking with your health care provider to see if they think it’s appropriate for you to use the Fringe Pelvic Health Wand. They can assess your unique health needs and determine if light and vibration therapy is right for you. However, we do know that it’s a great tool to use postpartum when it may help to support healing and recovery of pelvic tissues. Co-Author Elizabeth Frey, FCAMPT, MCISC (MANIP), MSc. PT, MSc, BPHE, BSc, MCPA - Fringe Pelvic Health Advisor Liz holds a BSc and BPHE from Queen’s University; a MSc in Exercise Physiology from the University of Toronto, a MSc (PT) from McMaster University, and a MCISC (Manip) from University of Western Ontario. Liz is a clinic owner and practicing physiotherapist with a specialty in pelvic health physiotherapy. She is a clinical lab facilitator at the University of Toronto, and a clinical supervisor for physiotherapy students. As an orthopaedic and pelvic health physiotherapist, Liz integrates her over 10 years of clinical expertise to provide a unique whole-body approach to wellness. Liz’s practice focuses on helping women navigate pregnancy, menopause, and everything in between. The contents in this blog; such as text, content, graphics are intended for educational purposes only. The Content is not intended to substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your healthcare provider.
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Should I Take a Magnesium Supplement?
Should I take a magnesium supplement? The simple answer to this question is: Most likely, yes. Scientific evidence suggests that many people are at risk of magnesium deficiency, even those consuming a healthy diet. There are many reasons for this, most of which are out of our control. Given the critical importance of magnesium in the human body, and the significant health risks that accompany even a subclinical magnesium deficiency, regular supplementation with a high-quality dietary supplement is a wise investment in your health. shop fringe magnesium What is Magnesium? Magnesium is one of the most abundant minerals, both in the earth and inside the human body. Most magnesium in the body is found inside cells, rather than in the blood, and it is especially concentrated in the muscles and bones. In the body, magnesium carries a positive charge, and is therefore referred to as an ion or electrolyte. The recommended intakes of magnesium have been determined and are based on age and gender. These values are known as the dietary reference intakes (DRI’s). Recently, it has been suggested that the DRI’s for magnesium are too low because they haven’t been adjusted for rising body weights. The new estimates recommend an additional intake for adults of between 60-235mg magnesium per day beyond what is shown in table 1. What does magnesium do in the body? Magnesium is involved in virtually every cellular metabolic and biochemical process in the human body. As a cofactor or activator for over 800 chemical reactions, magnesium regulates everything from metabolism to protein synthesis, to DNA repair and synthesis. It is also involved in conveying messages between molecules within the cell as well as in regulating cell replication. What are good sources of magnesium? Magnesium is found in many foods, both plant and animals. Some good sources of magnesium are: Green leafy vegetables Legumes Nuts Seeds Whole grains Good sources of magnesium should contain around 40-80mg per serving. Meat, dairy and fruit also contain some magnesium but at lower amounts. A general rule of thumb is that the more highly processed a food, the less magnesium it will contain (unless it has been fortified). Although there are many food sources of magnesium, a drastic loss of magnesium from agricultural soil over the last century has led to a decrease in the magnesium content of plant foods due to their inability to absorb sufficient magnesium from the earth. For example, the magnesium content of vegetables has decreased by 80-90% over the last century. As a result, supplementation with magnesium may be necessary to avoid deficiency. What is the prevalence of Magnesium deficiency? There are two types of nutrient deficiencies, frank and subclinical. Frank deficiencies have obvious signs, while subclinical deficiencies do not. Frank deficiencies of magnesium are rare because the kidneys can limit its excretion. But subclinical deficiencies are extremely common, since over half of the US population don’t consume the recommended amount. In fact, according to a research article in the Open Heart medical journal, “the evidence in the literature suggests that subclinical magnesium deficiency is rampant and one of the leading causes of chronic diseases including cardiovascular disease and early mortality and should be considered a public health crisis.” What are the causes of Magnesium deficiency? As already described, two of the main causes of magnesium deficiency are (1) low intake of dietary magnesium, and (2) a substantial loss of magnesium from agricultural soil causing a decrease in the magnesium content of foods. These two issues will be compounded, such that even when people attempt to consume sufficient dietary magnesium, they may be unable to. There are also several other factors that increase the risk of magnesium deficiency. These include: Magnesium also interacts with other nutrients, which can increase the risk of deficiency. For example, taking high doses of vitamin D can increase the loss of magnesium from the body, while taking high doses of zinc can interfere with magnesium absorption. High doses of fiber can also interfere with magnesium absorption. What are the health risks of Magnesium deficiency? Because of its nearly ubiquitous role in the body’s processes, low levels of magnesium can create widespread physiological dysfunction. And because of the widespread incidence of low magnesium intake, magnesium deficiency is recognized as an important global concern. A frank magnesium deficiency will manifest with clinical signs, including: Low appetite Nausea and vomiting Fatigue and weakness Muscle spams or tremors Abnormal heart rhythm Convulsions Psychiatric disturbances But because the kidneys regulate the excretion of magnesium from the body, it’s rare to have magnesium be depleted to the point where these potentially life-threatening symptoms occur. Far more common is subclinical magnesium deficiency, which often does not have obvious signs. Because it’s so easy to under consume magnesium, and since the signs of subclinical magnesium deficiency are hard to spot, it often extends over time leading to long-term adverse complications. These include a wide range of health problems and chronic diseases, including: Cardiovascular diseases Diabetes Migraines Osteoporosis Asthma Metabolic disorder Alzheimer’s Disease Parkinson’s Disease Premenstrual Syndrome Dysmenorrhea These conditions have potentially devastating consequences, which makes magnesium a critical nutrient of concern for public health. How could taking a magnesium supplement help me? There are both long-term and short-term benefits to ensuring adequate magnesium intake, which for many people, will require taking a magnesium supplement. As just described, there is a long list of health problems and chronic diseases associated with a long-term subclinical magnesium deficiency, many of which can be helped by taking a magnesium supplement. Can I take too much magnesium? Magnesium toxicity is mostly seen with consumption of high doses of magnesium containing laxatives and antacids. Consumption of more than 5000mg per day can cause toxicity, with symptoms including low blood pressure, nausea, vomiting, muscle weakness, and even cardiac arrest. It would be nearly impossible to consume this much magnesium through dietary supplements, which usually contain less than 300mg per serving, and totally impossible through food. Because the excretion of magnesium is regulated by the kidneys, it is difficult to take too much, and is not a concern except with consumption of magnesium containing medications. How do I choose a Magnesium supplement? Read the ingredients - Most dietary supplement will contain both active and inactive or “other” ingredients. You need to pay attention to both. The active ingredients are the ones that you are looking for; for example, a magnesium supplement will contain at least one form of magnesium as the active ingredient. Some supplements, like multi-vitamins, have many active ingredients. Usually, these are vitamins, minerals, of phytochemicals derived from plants. Although this information may be hard to find, it’s helpful to know where these active ingredients are sourced from. Naturally sourced ingredients are always better than artificial ones. The inactive ingredients are usually there to: (1) provide bulk (filler), (2) hold the product together (binding agents, coatings), (3) add flavor or sweetness, or (4) keep the product from clumping together (flow enhancers). Sometimes this list is long, and it’s often where some undesirable ingredients sneak in, such as potassium sorbate, artificial colors, or titanium dioxide. It’s best to keep this list short and naturally sourced. Verify product purity – Only choose high quality products that verify their purity via an unbiased chemical analysis performed by a third-party lab. These analyses should be reported in a Certificate of Analysis (COA) that is readily available to consumers, often through a QR code link. COA’s should be available for each batch of products, and will measure contaminants such as heavy metals, microbes, and pesticides. Consider the form(s) of magnesium in the supplement – There are several different forms of magnesium that are included in dietary supplements, each of which has unique properties. Look for ones that are bioavailable and easy on digestion. The forms of magnesium that are most likely to cause diarrhea are magnesium chloride, carbonate, oxide, and gluconate. Magnesium malate shows high bioavailability compared to the commonly supplemented forms of magnesium oxide and magnesium citrate. Other organic forms of magnesium such as magnesium glycinate and magnesium orotate also show high bioavailability. Some forms of magnesium have also shown unique health benefits; for example, magnesium orotate helps with cardiovascular and gut health. While all magnesium supplements can help to prevent magnesium deficiency, some forms may be better suited to your unique needs. Choose the supplement form you prefer – Supplements come in three main forms: capsules/tablets, powders, or liquids. Which one you choose is really a personal preference. Powders and liquid can be added to liquids, like smoothies, and are a great option if you don’t like swallowing pills. Fringe Essentials Magnesium Powder The Fringe Essentials Magnesium Powder contains three forms of magnesium: orotate, malate, and glycinate, at 173mg total and 41% of the recommended Daily Value. These forms of magnesium have been shown to be better absorbed into the body, and they’re easily digested. Each one has unique health benefits that make them well suited to not only ensure sufficient magnesium intake, but also to reap a wide range of health benefits. Here’s what they do: + magnesium glycinate: Magnesium glycinate is a standout in helping to reduce anxiety, promote relaxation, support deep sleep, reduce muscle tension, and balance mood. _____________________________________ + magnesium orotate: Magnesium orotate is one of the best forms of magnesium to consume for heart health. It’s been shown to help with hypertension and heart disease, and to reduce risks of heart attacks. It also supports gut and mental health and helps with exercise recovery. It may even be helpful in diabetes and Alzheimer’s Disease. _____________________________________ + magnesium malate: Magnesium malate is great for chronic pain, inflammation, energy production, and muscle tension and recovery. _____________________________________ The other ingredients in Fringe magnesium powder are all natural, and include non-GMO inulin to help with dosing, organic monkfruit extract for a bit of natural sweetness, and vitamin C for an antioxidant boost. Simply mix 1 scoop of magnesium into your water, smoothie, or favorite beverage 1-2 times per day. shop fringe magnesium
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Light Therapy for Inflammation
Inflammation is one of the most popular topics in healthcare, and rightfully so. It is a hallmark of many diseases currently ravaging modern society, such as arthritis, ulcerative colitis, inflammatory bowel disease, heart disease, diabetes, cancer, Alzheimer’s Disease, and depression. Inflammation is also associated with acute diseases involving the heart, pancreas, liver, and other organs, as well as trauma and infection. The personal and economic burden of these diseases cannot be overstated. Treatment of inflammation associated diseases makes up the majority of health care spending in the US, costing billions of dollars annually. There are also indirect costs of illness, such as reduced work and productivity. The most common treatments for inflammation are pharmaceuticals, including prescription (such as Celebrex) and the over-the-counter drugs (such as Aspirin and Alleve). However, many of these drugs have serious side effects, such as hypersensitivity reactions and ulcers. Given these risks, many people are turning to non-invasive therapies to fight inflammation, some of which are highly effective and have far fewer side effects than their pharmaceutical counterparts. One of these is treatment with red and near infrared light (also called red light therapy or photobiomodulation), which uses light waves at specific frequencies to decrease inflammation at a cellular level. Red Light Therapy The term “red light therapy” usually describes the use of both red and near infrared light, although only the red light produced by the device is visible to the naked eye. Infrared light can still be perceived by the body as heat when it contacts skin. Red and near infrared light therapy is the application of artificially generated light in the red and near infrared spectral bands. Red and near infrared light are naturally produced by the sun, which gives off solar radiation. The term radiation describes energy that is transmitted in the form of waves or particles. The spectrum of light in our environment consists of both light we can see (visible light) and light that our eyes can’t perceive (invisible light). This is called the electromagnetic spectrum. The visible light spectrum is quite narrow, consisting of wavelengths that range from 400 to 700nm and span from violet to red in color. Red light is part of this visible light spectrum, while near infrared light is not. While early research on light therapy used primarily lasers, more recent research has found that LED’s can also be used, which also have the advantage of applying light to a larger area of the body as well as an improved safety profile. The use of LED in red/near infrared light therapy devices has also greatly reduced the cost of treatment, making it something that can be done in the comfort of one’s own home. Inflammation The inflammatory process is mediated by the immune system, specifically the innate (or non-specific) component. Inflammation protects the body from injury and infection. There are many goals of the inflammatory response, including reducing the extent of injury, limiting the spread of infection, and restoring the body back into balance. While we mostly think of inflammation as being harmful, it’s actually a natural and essential physiological function. Inflammation becomes harmful when it is uncontrolled, lasts for a long time, or just generally occurs when it shouldn’t. There are three types of inflammation, which are mainly defined by their length. Acute inflammation is short term, lasting days. This is what happens when you sprain your ankle, and it swells up, becomes warm, and may show color changes. That response is designed to limit movement, which prevents further injury and allows the damaged tissue to heal. Sub-acute inflammation lasts from two to six weeks, and often follows acute inflammation as healing progresses. The response here is similar, but less intense, than acute inflammation. Chronic inflammation lasts for months or even years, and at this point, inflammation has ceased to be a normal (and healthy) response to a stimulus and has become pathological. Chronic inflammation is the type that is associated with most diseases. It is also associated with oxidative stress. Chronic inflammation is not associated with visible signs of inflammation (such as redness, heat, and swelling), so people often aren’t even aware it is happening. This contrasts with acute inflammation, which is usually visible and occurs because of trauma or infection. Red Light Therapy for Inflammation As described by Dr. Michael Hamblin, former Associate Professor at Harvard Medical School, “one of the most reproducible effects of is an overall reduction of inflammation”. Studies have found that light therapy affects levels of many molecules involved in inflammation, including reactive oxygen species, reactive nitrogen species, and prostaglandins. Light therapy has even been found to reduce inflammation in the brain, known as neuroinflammation. Red light therapy has been shown to have anti-inflammatory effects in the following conditions: Brain Disorders – Neuroinflammation is one of the foundational pathologies underlying a wide range of brain disorders. Light therapy has been found to decrease inflammation in Alzheimer’s Disease, as well as to improve cognitive function. Several clinical trials have been published which have shown positive results. Most studies have exclusively used near infrared light, which has been found to penetrate more deeply into the brain. Light therapy has also been found to decrease inflammation and improve recovery after a stroke. When used to treat brain disorders, light therapy is usually applied to the head area, using devices such as hats and helmets. Traumatic Brain Injury - Traumatic brain injuries (TBI) occur when there is a violent blow to the head. Approximately 17% of people with repeated TBI progress to chronic traumatic encephalitis (CTE), a brain disorder caused by repeated head injuries. Concussions are another common type of TBI. TBI’s result in acute neuroinflammation, which can become a chronic problem if not treated properly. Research using light therapy (both red and near infrared) for TBI has looked at both immediate and chronic effects in animal and human models. Animal studies have shown a reduction in the size of the brain lesion when light therapy was applied to the head immediately following trauma, which correlated with the severity of neurological symptoms, which may be due (in part) to decreased inflammation. Depression – Neuroinflammation is similarly found in people suffering from depression, and it is thought to be a key factor and therapeutic target in depressive disorders. Several clinical trials of light therapy in depression have been conducted, all of which used near infrared light applied directly to the head. A 2022 systematic review concluded that light therapy “can be classified as strongly recommended for moderate grade of major depressive disorder”. Similarly, a 2023 meta-analysis concluded that there is a “promising role of in the treatment of depressive symptoms”. Gut Disorders – Inflammatory gut diseases like colitis and inflammatory bowel diseases may benefit from red light therapy. Research has found that application of red light to the abdomen of rats with experimentally induced colitis (a form of inflammatory bowel disease) improved many markers of gut health, including reducing inflammation. There is interest in studying the use of light therapy to improve gut health in human subjects as well, with research currently ongoing to see if it helps patients with inflammatory bowel disease. When treating gut disorders, light therapy is usually applied directly to the abdomen. Pain - Pain creates a huge burden of disability, both personal and economic. There is evidence that red light therapy decreases many types of pain, including knee, neck, low-back, temporomandibular joint, and post-surgical pain. Red light therapy can also reduce pain associated with arthritis and fibromyalgia. One of the primary mechanisms of pain reduction by light therapy is by decreasing inflammation. Red light therapy also reduces pain by decreasing oxidative stress, reducing the sensitivity of neurons, and decreasing the transmission of pain related nerve impulses. Arthritis – In addition to reducing arthritis pain by decreasing inflammation, the anti-inflammatory effects of red light therapy on arthritis also yields other benefits. Inflammation in arthritis is responsible for much of the observed pathology, including cartilage breakdown. Treatment with red light therapy may have a range of positive effects, such as preserving joint function, avoiding joint deformities, and reducing drug side effects and toxicities. Delayed Onset Muscle Soreness – Delayed onset muscle soreness (DOMS) is pain that occurs in the muscles between 12 and 24 hours after a workout. DOMS is caused by tiny muscle tears that results in inflammation, which causes pain. Treatment with red light therapy to muscles after a strength training session has been shown to decrease markers of inflammation, as well as to improve other outcomes like decreased fatigue and increased protein synthesis. Injury – In addition to its anti-inflammatory effects on muscle tissue, including speeding recovery from post-exercise damage, red light therapy also reduces inflammation and speeds wound healing, such as from burn injuries. Red light therapy can also reduce inflammation and speed healing from injuries to bone, including fractures and more complex bone injuries that require the use ceramic materials. Tendon injuries also benefit from red light therapy. Skin Disorders – Many skin disorders are characterized by inflammation, including acne, psoriasis and eczema. Light therapies treat acne through anti-inflammatory and antimicrobial effects, and by decreasing the production of oil. Inflammatory acne is more responsive to light therapy than non-inflammatory acne, and studies have even found it to be superior to some medications. Red and near infrared light is also recommended in the treatment of psoriasis in part because of its anti-inflammatory effects. And in eczema, an inflammatory skin disease, treatment with near infrared light therapy has been found to decrease skin itching and lesions. Alopecia Areata – Alopecia Areata (AA) is an autoimmune disease that causes the body to attack its own hair follicles. This causes the hair to fall out, resulting in patches of baldness. AA can affect hair on any part of the body but is most common on the head. It is characterized by inflammation around hair follicles during the growth phase. The anti-inflammatory effects of light therapy may decrease this inflammation. In fact, treatment with red and near infrared light has been found to increase hair growth in bald patches. How To Use Red Light Therapy To Reduce Inflammation There is no single right way to use red light therapy to reduce inflammation. It all depends on what condition you are trying to treat and what your personal preferences are as far as treatment approach. The following are a few simple questions that can be used to guide you towards selecting the device that is most suitable for your needs: 1. What are your specific health concerns? Red light is usually applied to the affected body part, either directly in contact with the skin or at a distance of around 4 to 12 inches away. Some devices are location specific, such as knee wraps, head wraps or helmets, shoulder and neck wraps, or elbow and wrist red light wraps. Other devices are non-specific, such as square or rectangular light wraps, or red light panels. If you are dealing with a single, region-specific concern – such as knee arthritis or Alzheimer’s Disease - you may prefer to get a regionally targeted red light therapy device. However, if you are dealing with inflammation in more than one area of the body and want a device that can be used in multiple locations, a non-specific wrap may be preferable. Red light panels can also be used to address multiple body parts, although they may be difficult to position properly for some locations, such as the feet and ankles. 2. What are your preferred treatment conditions? Treatments using red light panels are most often done in a seated position, with the panel oriented towards the face, neck, torso, or other affected body part. They can also be done in a standing position, although this is not as relaxing. Lying down is possible if the treatment location allows it. Red light panels are wired and require the user to stay in the same position throughout the duration of the treatment. In contrast, treatments using red light wraps can be done in any position, including standing, sitting, and lying down. They can even be worn while moving around. Some red light wraps are wired, while others are wireless, with wireless models providing more flexibility. 3. What device specs should you look for? At home red light therapy devices almost always use LED’s as the light source. However, they do vary in other parameters, such as light wavelength(s) and intensity. When it comes to choosing the optimal wavelengths, you should look for light in the red and/or near infrared spectrums - but avoid the range of 700-780nm which has been found to be ineffective. Multi-wavelength devices including both red and near infrared light may be the most versatile. In terms of intensity, it has been found that it is ideal to mimic the intensity of the sun, which is around 24 mW/cm2 at the skin. This is described as the “sweet spot” between higher intensities, which can have harmful effects, and lower intensities, which will have no effect at all. Many devices on the market are at a much higher intensity than the sun, so choose a sun-mimicking product and don’t overdo it when it comes to treatment frequency and duration. Conclusion Red light therapy (with red and near infrared light) may be used to reduce inflammation in a wide range of diseases, both acute and chronic. There are very few contraindications to red light therapy, and it can be safely used at home as part of a regular wellness regime. Choose a device that suits your needs and preferred treatment conditions, and which delivers both red and near infrared light at an appropriate intensity. Combine red light therapy with an anti-inflammatory diet and supplements, regular exercise, stress management, and good sleep hygiene for best results. For more information about Fringe light products, go to: https://fringeheals.com/shop-all-products/
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Red Light for Arthritis
Arthritis refers to a group of diseases that are characterized by inflammation. Inflammation (also known as swelling) can cause both pain and stiffness. The two main types of arthritis are osteoarthritis – where joint damage causes inflammation – and inflammatory arthritis – where inflammation itself causes joint damage. Most inflammatory arthritis conditions are autoimmune in nature. Arthritis can affect any joint in the body, but is most common in the hips, knees, and spine. For years, anti-inflammatory and pain-relieving pharmaceuticals were used as first-line therapies for arthritis, with natural therapies viewed as being less effective. However, the widespread use of opioids resulted in an epidemic of addiction that necessitated the search for new ways to deal with pain. These medications also have side effects such as GI bleeding. Given these risks, many people are turning to non-invasive therapies to fight arthritis, some of which are highly effective and have far fewer side effects than their pharmaceutical counterparts. One of these is treatment with red and near infrared light (also called red light therapy or photobiomodulation), which uses light waves at specific frequencies to decrease inflammation at a cellular level. As described by Dr. Michael Hamblin, former Associate Professor at Harvard Medical School, “one of the most reproducible effects of is an overall reduction of inflammation”. Studies have found that light therapy affects levels of many molecules involved in inflammation, including reactive oxygen species, reactive nitrogen species, and prostaglandins. This makes red light therapy well suited to treat both osteo- and inflammatory arthritis. In addition to reducing arthritis pain by decreasing inflammation, the anti-inflammatory effects of red light therapy on arthritis also yields other benefits. Inflammation in arthritis is responsible for much of the observed pathology, including cartilage breakdown. Treatment with red light therapy may have a range of positive effects, such as preserving joint function, avoiding joint deformities, and reducing drug side effects and toxicities. Fringe makes many red light products that can be used to treat arthritis, including joint wraps, rectangular wraps, and red light panels. If you are dealing with a single, region-specific concern you may prefer to get a regionally targeted red light therapy device, like the Fringe Knee/Foot/Ankle or Elbow/Wrist Wrap. However, if you are dealing with arthritis in more than one area of the body and want a device that can be used in multiple locations, a non-specific wrap (like the Fringe Red Light Therapy Wrap or Extra Long Wrap) may be preferable. The Fringe Red Light Panel can also be used to address multiple body parts, although it may be difficult to position properly for some locations, such as the feet and ankles. There are very few contraindications to red light therapy, and it can be safely used at home for the treatment of arthritis. Choose a device that suits your needs and preferred treatment conditions, and which delivers both red and near infrared light at an appropriate intensity. Combine red light therapy with an anti-inflammatory diet and supplements, regular exercise, stress management, and good sleep hygiene for best results. For more information about Fringe light products, go to: https://fringeheals.com/shop-all-products/
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Red Light Therapy for Gut Health
The Human Gut The human gut, also known as the gastrointestinal tract (GI tract), consists of the esophagus, stomach, small intestine, and large intestine. In simple terms, it is a tube or passageway for food that passes from the mouth to the anus. Each part of the gut has its own job to do, which is usually described as the digestion and absorption of food, and the excretion of digestive waste products. In recent years, however, a critical new role has emerged for the human gut, specifically the large intestine. As the last part of the GI tract, the large intestine receives food after most of the nutrients are absorbed and functions to reabsorb water and some remaining minerals. While this final step in the processing of food is essential, equally (if not more) important is the role of the large intestine as host to the gut microbiome, which is being described as a “major determinant of health.” The Gut Microbiome The human body contains over 150 times more genes from resident microorganisms (such as bacteria, viruses, and fungi) than from its own human cells. With a total weight of just over 2kg, microbial cells outnumber human cells by around 10 to 1. Most of these organisms went unrecognized until the last two decades. However, we now know that the body is literally teeming with invisible inhabitants, which comprise what is referred to as the human microbiome. The combined human and microbiome genome is referred to as the “holobiome”. The term “resident” is an apt descriptor when it comes to the microbiome. These organisms live inside the body, from birth to death. They also reside on the surface of the skin. And while the germ theory of disease has conditioned us to believe that most microorganisms are pathological, in fact the human microbiome is one of the most important biological predictors of health. The opposite is also true: alteration in the microbiome is an important predictor of disease. The microbiome communicates with the body, and the body communicates with the microbiome. This crosstalk is essential for human health. The human microbiome can be broken down into several divisions, based on location. The microbiome that lines the mouth is the oral microbiome; the microbiome that lines the skin is the cutaneous microbiome; the microbiome that lines the vagina is the vaginal microbiome; and the microbiome that lines the digestive tract is the gut microbiome. The gut microbiome is the most well researched biome. The role of the gut microbiome is complex and spans a wide range of diverse functions. Gut microbes are involved in the metabolism of carbohydrates, lipids, and proteins, and help to extract nutrients from food. In the gut, they produce useful molecules such as short chain fatty acids and vitamin K. Gut microbes also manufacture neurotransmitters such as serotonin, and through the gut brain axis, regulate many aspects of cognitive function. The microbiome is also involved in the metabolism of ingested drugs and toxins. The gut microbiome starts its development in utero and continues throughout the fetal period, with further colonization during delivery. Most gut microbes are acquired post partem, with breast milk as an important source in early life. A diet containing predominantly plants and whole foods is considered optimal to support the gut microbiome, with fiber being of utmost importance. Processed food, food that is high in sugar, and low fiber diets are bad for gut health. It has been recommended that dietary guidelines be revised to support a healthy gut microbiome. In addition to diet, there are several other factors that influence the health of the gut microbiome. According to the Canadian Digestive Health Association, non-dietary ways to strengthen the microbiome including: avoiding antibiotics, regularly sleeping for at least 8 hours per night, getting regular exercise, and engaging in stress reducing activities. Evidence is also accumulating that gut microbiome health can be supported by therapy with red and near infrared light. Light Therapy Light therapy (also known as photobiomodulation) is the application of light with specific wavelengths to the body for the purposes of influencing biology. The most common form of light therapy uses red light (RL), which is visible as the color red, and/or near infrared light (NIRL), which is not visible but can be felt as heat. The RL used in light therapy usually ranges from 600 to 700 nanometres (nm), with the unit nm referring to distance the light wave travels in one cycle. The NIRL used in light therapy usually ranges from 800 to 900nm. RL and NIRL are naturally produced by the sun, which gives off solar radiation. The term radiation describes energy that is transmitted in the form of waves or particles. The spectrum of light in our environment consists of both light we can see (visible light) and light that our eyes can’t perceive (invisible light). This is called the electromagnetic spectrum. The visible light spectrum is quite narrow, consisting of wavelengths that range from 400 to 700nm and span from violet to red in color. RL is part of this visible light spectrum, while NIRL is not. Red and near infrared light therapy is the application of artificially generated light in the red and near infrared spectral bands. The term “red light therapy” usually describes the use of both RL and NIRL, although only the red light produced by the device is visible to the naked eye. IRL can still be perceived by the body as heat when it contacts skin. How Does Red Light Therapy Affect Gut Health? Red light can affect gut health both through effects on the microbes in the microbiome, as well as on the gut cells of the human host. It’s hard to tease out precisely what is happening in this complex microenvironment, but one thing is clear: light therapy administered to the gut has a positive biological effect. Research has indeed shown that light can modify the microbiome. For example, when RL or NIRL was applied to the abdomen of mice, the composition of the microbiome shifted to include more of a bacterial strain that is associated with better health. Bacteria have also been found to respond to the direct application of RL. Light therapy also impacts human cells. Light is absorbed in cells by molecules called chromophores, many of which are found inside the mitochondria. Mitochondria are the powerhouses of the cell, which make the energy currency of the cell known as ATP. Mitochondria are also involved in regulating the production of molecules called reactive oxygen species (ROS), which play a role in normal cellular function but can be harmful in high amounts. This is known as oxidative stress. Through its effects on mitochondria, light therapy can increase cellular energy production and modulate oxidative stress. Intestinal oxidative stress is associated with disease. Through effects on cellular metabolism and ROS production, as well as through reduction of other molecules such as reactive nitrogen species and prostaglandins, light therapy can decrease inflammation. Both RL and NIRL have anti-inflammatory effects, and unlike anti-inflammatory medications (such as NSAID’s), do not cause side effects. Inflammation is a hallmark of many gut disorders, such as Crohn’s Disease and Ulcerative Colitis. By improving the health of the gut (both the microbiome and human gut cells), a wide range of positive effects are observed, including: Improving communication between microbiome and the rest of the body. Improving digestion of food and production of energy and nutrients. Decreasing inflammation and production of reactive oxygen species. Increasing production of short chain fatty acids involved in immune function. Improving the health of the gut lining. Gut Dysbiosis When the gut microbiome is dysregulated, there is an adverse effect on its human host. This is called gut dysbiosis. Poor dietary choices, sedentary lifestyle, increased stress, and use of antibiotics (and other pharmaceuticals) can cause the gut microbiome to become unhealthy. This causes a loss of integrity of the gut lining, also known as leaky gut. In turn, the gut becomes permeable to things like microbes and food fragments, which activate the immune system and trigger an inflammatory response. Chronic inflammation ensues, and a vicious cycle is established in which the gut becomes increasingly compromised, which worsens the inflammation. Dysbiosis also impairs metabolism. Gut dysbiosis has been associated with an enormous range of human disease, including metabolic syndrome, neurological disorders, immune system disorders, autism, psychiatric disorders, obesity, systemic inflammation/autoimmunity, type 2 diabetes, chronic pain, multiple sclerosis, inflammatory bowel disease, and eye diseases. A 2021 article in The Guardian described that “The great opportunity – but also the great difficulty – of gut microbiome science is that poor gut health is associated with such a vast range of conditions.” This means that there is enormous potential to reduce human disease by improving the health of the gut microbiome, although it is important to acknowledge that our understanding of these relationships is still limited. Clinical Applications of Light Therapy to the Gut The use of light to improve health dates back thousands of years. Sunlight has been used in medicine since at least the time of the Ancient Greeks, to treat conditions such as tuberculosis, skin disorders, and bacterial and fungal infections. However, the practice fell out of favor during the 20th century as modern societies embraced the medical pharmaceutical model of therapeutics. Over the last decade, there has been an increasing interest in harnessing the power of light as a therapeutic, and a wide range of applications are being explored. Several studies have investigated what happens when RL and/or NIRL light is applied to the abdomen. Interestingly, the bulk of this research has been done using abdominally applied light to treat brain disorders, rather than for GI tract diseases. This is because of the important relationship between the gut microbiome and the brain, through a pathway known as the gut-brain axis (GBA), which involves bidirectional communication between the gut (including the microbiome) and the brain. The GBA plays an important role in brain, gut, and immune health. Alterations in the gut microbiome may be associated with disease through the GBA. RL and NIRL applied to the abdomen (as well as the neck, head and nose) of Parkinson’s disease (PD) patients has been shown to modulate the composition of the gut microbiome, with a shift towards more “healthy” bacteria. Light applied to the abdomen and neck for 12 weeks also decreased symptoms such as impaired mobility in PD patients, with improvements lasting for up to a year. PD is a degenerative brain disease that causes motor symptoms (such as balance and gait problems) and non-motor symptoms (such as depression, sleep disorders, and cognitive impairment). It affects around one million people in the US, and over 10 million people globally. Application of RL and NIRL to the abdomen (as well as the head) has also been used in the treatment of Alzheimer’s Disease (AD). In a 2022 clinical trial of patients with mild to moderate AD, those receiving light therapy showed improved cognitive function relative to the control group. Alzheimer’s Disease (AD), a form of dementia, is a neurodegenerative disease that comprises 70% of dementia cases. AD affects 1 in 10 US adults over the age of 65, or 5.7 million Americans. It has been suggested that light therapy applied to the abdomen may be useful in reducing depression. The composition of the gut microbiome has been linked to depression, with depressive patients showing higher levels of certain bacteria that are involved in the synthesis of neurotransmitters such as serotonin and GABA. These neurotransmitters are involved in the regulation of mood. Gut microbiome composition has been strongly associated with mental well-being. Given the associations between brain diseases and the GBA, it has been suggested that targeting the microbiome holds great potential in the treatment of neurodevelopmental and neurodevelopmental diseases. In addition to AD and PD, these include diseases such as multiple sclerosis, autism spectrum disorder, attention-deficit hyperactivity disorder, migraine, post-operative cognitive dysfunction, and long COVID. According to researchers from Australia, many studies are currently underway “with the aim of restoring the microbiome and potentially altering the course of these brain conditions.” Light therapy may also be helpful in modifying the microbiome in diseases that primarily affect other body systems. For example, in a case report of a patient with breast cancer, application of NIRL to the abdomen was associated with increased diversity of gut microbes, which is considered to be a healthy change. The authors suggest that light therapy may be a way to improve gut health in patients with chronic disease. Most patients with chronic disease use medications which may adversely affect gut health (especially the microbiome). There is also great potential to use light therapy to treat gut disorders. For example, animal research has found that application of RL to the abdomen of rats with experimentally induced colitis (a form of inflammatory bowel disease) improved many markers of gut health, including reducing inflammation. There is interest in studying the use of light therapy to improve gut health in human subjects as well. Notably, a study using NIRL applied to the abdomen (as well as the front of both thighs) is currently underway to assess whether treatment reduces pain, fatigue, and depression in patients with inflammatory bowel disease. Effects on the gut microbiome will also be measured. Using Light Therapy for Gut Health There are many light therapy devices on the market today that could be used at home to target gut health. With so many options available, how can you know which device is best for you? Here are five issues to consider. Style Preference: To treat the gut with light therapy, light should be applied to the abdominal area. Two types of devices are most appropriate for abdominal applications: (i) a light panel, or (ii) a light wrap. Your personal level of comfort with a device is important. Imagine yourself using it – Do you want to stand in front of the device, or would you prefer the flexibility of being able to lie down while wearing it? Do you want a device that is wireless, or can you commit to being close to an electrical outlet so that you can plug it in? Think about your personal preferences and choose accordingly. Laser vs LED: Light therapy is administered using either laser or LED lights. While early light therapy research was done using lasers, LED lights have become much more popular over the last decade. The research described in this article includes both types of light sources. In 2018, Dr. Michael Hamblin – the world’s leading light therapy expert – concluded that LED lights using comparable parameters to lasers performed “equally well”, which is very important because LED powered light therapy devices can be made at a fraction of the cost of laser devices. For at home use, look for a device that uses LED lights as safe and affordable option. Light Color/Wavelength – As described in this article, both RL and NIRL have been used in studies of light therapy to treat gut disorders. Positive results have been observed when these wavelengths were used either together or individually. So, look for products that use RL and NIRL either alone or in combination. Light Intensity – Light intensity refers to the amount of light being delivered by a device. It is also referred to as irradiance. The required intensity when using light therapy to impact gut disorders is unclear. There is variability in light intensity between studies, and no studies have directly compared different intensities. Since light is being delivered to the skin of the abdomen, it may be prudent to follow the advice given for light therapy to the skin, and mimic the intensity of the sun, which is around 24 mW/cm2. This is described as the “sweet spot” between higher intensities, which can have harmful effects, and lower intensities, which will have no effect at all. Placing a high intensity device directly on the skin could be harmful. Choose a sun-mimicking product and don’t overdo it when it comes to treatment frequency and duration. Education – While light therapy education will not change the specific functionality of a device, it does have the potential to profoundly impact how someone uses the technology. When a company provides evidence-based education that teaches consumers why, how, and when to use a product, devices can be used to better support healing. Look for products with accompanying education and instructions for use, whether in printed and/or digital formats. You can also look for companies that provide support by phone or email to current or prospective customers. Conclusion Hippocrates is credited with stating that “All disease begins in the gut”. While today’s science does not yet support that level of conviction, we do know that gut health is intimately associated with the overall health of the human body. We also know that “what happens in the gut doesn’t stay in the gut”, but rather influences other organs and systems through complex communication networks. The gut microbiome is inextricable from our own human gut, and both are important for optimal health. When using light therapy for gut health, it’s important to also engage in other gut-friendly activities. These include eating a gut healthy diet, staying hydrated, exercising regularly, and limiting stress. It’s advisable to work with a health care provider with expertise in this area and who can provide appropriate support. Many questions remain about how light therapy can be used to support gut health, but preliminary pre-clinical and clinical evidence supports the use of RL and NIRL both to induce healthy shifts in the gut microbiome and to decrease inflammation. Since RL and NIRL also have other effects, such as increasing energy and decreasing ROS production, many other benefits are likely to be observed. This is certain to be an area of active research interest, especially given the amazing safety profile of light therapy and the increasing availability of at-home devices. For more information about Fringe light products, go to: https://fringeheals.com/shop-all-products/
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Red Light Therapy for Seasonal Affective Disorder
What is Seasonal Affective Disorder (SAD)? Seasonal Affective Disorder (SAD) is also known as the “winter blues” or “seasonal depression”. In the simplest terms, it is depression that follows a season pattern, usually occurring in the winter. SAD is considered a variant of Major Depressive Disorder or Bipolar Disorder, rather than a distinct condition. It is recognized in the Diagnostic Manual of Mental Disorders (DSM-5) and affects around 5% of US adults. January and February are the hardest months for people with SAD. The symptoms of SAD are similar to the symptoms of non-SAD depression, and include: feeling sad fatigue and loss of energy loss in interest or pleasure in activities changes in appetite and sleep (especially overeating and oversleeping) feeling worthless or guilty difficulty thinking, concentrating, or making decisions physical aches and pains thoughts of death or suicide. SAD occurs at a specific time of year and the diagnosis requires that it recurs at least two consecutive years in the same season. Symptoms last for around 4 to 5 months, and there is full remission of symptoms when the season ends. SAD usually occurs in the Fall or Winter. Risk factors for SAD include being female, living at a northern latitude, a family history of SAD, and being between 18 and 30 years of age. Both pharmacological and non-pharmacological treatments have been identified as first line therapies for SAD. Pharmacological treatments include antidepressant medications, such as selective serotonin reuptake inhibitors. Non-pharmacological treatments include cognitive behavioral therapy and light therapy. The goal of light therapy is to compensate for the loss of natural sunlight during the shorter and darker winter months, and most often involves exposure to bright white light. What is the relationship between light and SAD? The seasonal nature of SAD and its high prevalence during the winter months, along with resolution during warmer, sunnier seasons, suggests a causal relationship with sun and light exposure. Human biology is clearly linked with the rhythm of the sun, with people naturally following a sleep/wake cycle that is associated with night and day. This sleep/wake cycle is also known as our circadian rhythm. Circadian rhythms are the “physical, mental, and behavioral changes an organism experiences over a 24-hr cycle.” In addition to light and dark, circadian rhythms are also influenced by temperature, diet, exercise, stress, and social environment. Light, however, is the primary regulator, and it exerts this influence through effects on the brain. The influence of light on the brain starts with the eyes. Light enters the retina and activates cells called intrinsically photosensitive retinal ganglion cells. Retinal ganglion cells are active even in people who are completely blind, who show similar sleep and wake cycles to sighted people because of the response of these cells to light. Retinal ganglion cells show their greatest response to the blue light spectrum. Sunlight contains blue light, in addition to many other wavelengths of color. From the eyes, a signal is sent to the suprachiasmatic nucleus in the brain. Known as the “master circadian clock”, the suprachiasmatic nucleus is the most important circadian regulator. The clock in turn sends out many signals that regulate a wide range of processes in the body, including controlling the expression of up to 10% of our genes. Light is the primary regulator of this internal clock, although there are other non-light influences on this rhythm too. Melatonin and cortisol are the main hormonal mediators of the circadian rhythm, and the synthesis of both is regulated by light. Melatonin is secreted in response to the absence of light, triggering sleep. Cortisol is secreted in response to the presence of light, triggering wakefulness. The synthesis of both melatonin and cortisol is controlled by signals that come from the suprachiasmatic nucleus. In the winter months, decreased exposure to light causes the circadian rhythm to shift later in the day, which results in a misalignment between the sleep-wake cycle and the circadian rhythms’ natural processes. Exposure to certain types of light on winter mornings pulls the circadian rhythm back into alignment. Different types of light are known to have variable effects on the circadian rhythm. Both bright white and blue light suppress the release of melatonin, which promotes wakefulness. Blue light exposure can cause the circadian rhythm to shift even when applied later in the day, unlike bright white light which is more effective at causing a shift in the morning. Red light does not suppress melatonin levels or cause the circadian rhythm to shift. These variable effects of different wavelengths (colors) of light have important implications for light therapy, which is the application of external light sources to affect biology. Exposure to light has been clearly shown to be associated with mood. A study of over 400,000 people showed that increasing exposure to daylight associated with reduced risk of major depression and greater happiness. This may be mediated by serotonin, which is known as a “natural mood booster”. Serotonin is a critical link and regulator of both the circadian rhythm and mood, and levels increase with sun exposure. In contrast to the positive mood effects of sunlight exposure, exposure to artificial light later in the day can have adverse effects. In simple terms, the naturally stimulating effect of white and blue light on wakefulness is helpful in the early part of the day but is harmful in the evening and at night. The associations between light and levels of melatonin, cortisol, and serotonin provide clues as to how the dark, short days of winter can negatively impact mood. And while more research is needed to clearly understand the pathology of SAD, its positive response to light therapy suggest that light is one of the most important mediators. How is red light therapy for Seasonal Affective Disorder used? Light therapy is widely accepted as a first line non-pharmacological treatment for SAD. Usually, this involves treatment with bright light (called Bright Light Therapy, BLT), but dawn simulation is also used. Dawn simulation delivers light that gradually increases during the last half hour of sleep, while BLT delivers very bright light (most often white, but sometimes blue) shortly after waking. Bright light therapy has been shown to be more effective for people with more severe depression, but both are beneficial. As already described, retinal ganglion cells in the eye respond to light, particularly in the blue spectrum. White light contains all visible light frequencies, including blue, and both white and blue light promote wakefulness, in part through suppression of melatonin. This is why white and blue light are the main sources of light used in SAD light therapy. Light intensity is measured in Lux, and bright light is typically considered to be at least 10,000 Lux. Light intensity varies greatly, sometimes in surprising ways. Here are some light intensities under different conditions: Bright sunlight = 120,000 Lux Bright sunlight = 110,000 Lux Shaded area on a sunny day = 20,000 Lux Overcast day, midday = 1,000 – 2,000 Lux Sunrise/Sunset (clear day) = 400 Lux Sunrise/Sunset (overcast) = 40 Lux Moonlight (clear night) = 1 Lux Office lighting = 200 – 400 Lux Home lighting = 50 – 200 Lux In BLT, an external light source (usually called a “light box”) is used that delivers light at around 10,000 Lux. It is recommended to use BLT in the early morning shortly after waking for approximately 30 minutes. The person should position themself 60-80cm from the light box, with the light at eye level. Lower intensity light can be used (2,500 - 5,000 Lux) but with lower intensity light the treatment duration is extended to 1 to 2 hours. Treatment should be done until the season ends. Light used in BLT will be delivered by either fluorescent or LED lights. Fluorescent lights deliver white light, either warm or cool, while LED lights can deliver both white and blue light. White light is referred to as “colorless daylight” and is made up of all the frequencies in the visible light spectrum (including red, yellow, green, blue, etc.). White fluorescent bulbs and LED lights will also contain all of the visible light frequencies but they can vary in their spectral characteristics, such as the particular wavelength distribution and intensity. When the spectrum of light from bright light devices is analyzed, it varies depending on the light source. Fluorescent lights, both warm and cool, emit light that shows several peaks that correspond to different colors, including red. White LED diodes usually have a sharp blue peak, but they also contain wavelengths of different colors. The main difference between white and blue BLT devices is that white light contains multiple colors (called polychromatic), even though it appears white or colorless, while blue light is a singular color (called monochromatic). It is sometimes claimed that SAD light boxes provide a “hefty dose” of blue light. This is not entirely true. The spectral analysis of devices that use both warm and cool fluorescent lights reveals a mixture of wavelengths (yes, including blue), but their calculated “blue light hazard” level is actually quite low. Warm fluorescent light is a bit better than cool fluorescent light, which showed around the same blue light hazard as white LED light. It’s also important to note that blue light is “disruptive” to the circadian rhythm precisely because our bodies are naturally designed to respond to the blue wavelengths of light from the sun. When used in the morning, exposure to blue light (even artificial) provides a cue for the system to wake up. It should go without saying that bright light therapy devices should not be used in the evening. BLT has been found to effectively reduce the symptoms of SAD, although white light shows more effectiveness than blue light. A meta-analysis published in 2015 found that bright white light therapy was effective, although the effects were weaker at some time points. A meta-analysis of bright blue light therapy for SAD did not find it to be beneficial. How Does Seasonal Affective Disorder Relate to Different Wavelengths of Light? SAD is related to the lack of daylight, or sunlight, during winter months. Sunlight consists of solar radiation, which is energy that is transmitted in the form of waves or particles. The spectrum of light in our environment consists of both light we can see (visible light) and light that our eyes can’t perceive (invisible light). This is called the electromagnetic spectrum. The visible light spectrum is quite narrow, consisting of wavelengths that range from 400 to 700nm and span from violet to red in color. Although the amount of solar radiation is not constant, approximately 40% percent of the light from the sun is visible light, which can be divided by color and wavelength. Near infrared light waves lie just beyond the “red” end of the visible light spectrum, so we don’t see them. Near infrared light is part of the “infrared” spectrum, which consists of both near infrared and far infrared light. Infrared light makes up 50% of the solar radiation that reaches the earth. The remaining 10% of the light from the sun is also invisible, falling just beyond the opposite “violet” end of the visible spectrum to IR. This is called ultraviolet light (UVL). What this means is that BLT only partly mimics the natural effects of sunlight, since it delivers only visible light. Bright white light does not include light in the UV spectrum of the sun. This is done intentionally, since UV rays are the component of solar radiation that are the main culprits in causing skin cancer. Bright white light also does not include light in the infrared spectrum of the sun. This omission is less justified, since infrared light does not have harmful effects on the skin (quite the opposite, in fact), and infrared light makes up a significant amount of natural sunlight. BLT that uses blue light excludes not only UV and infrared light but also the non-blue wavelengths of light, including red, orange, yellow, green and violet. Does Red Light Therapy Improve Seasonal Affective Disorder? Red and near infrared light therapy is the application of artificially generated light in the red and near infrared spectral bands. The term “red light therapy” usually describes the use of both red and near infrared light, although only the red light produced by the device is visible to the naked eye. Infrared light can still be perceived by the body as heat when it contacts skin. Like BLT, red and near infrared light therapy does not involve the use of UV rays. The red light used in light therapy usually ranges from 600 to 700 nanometres (nm), with the unit nm referring to distance the light wave travels in one cycle. The near infrared light used in light therapy usually ranges from 800 to 1100nm. Interestingly, there are no clinical trials of red light therapy to treat SAD, but there are many that have been done looking at the effects of red light on non-SAD depression. All of the non-SAD clinical trials of red light therapy used near infrared light applied directly to the head. A 2022 systematic review concluded that near infrared light therapy “can be classified as strongly recommended for moderate grade of major depressive disorder”. Similarly, a 2023 meta-analysis concluded that there is a “promising role of in the treatment of depressive symptoms”. These results demonstrate that red light therapy has positive effects on mood. Another challenging symptom of SAD is sleep disturbance, which is another issue that red light therapy has been found to help. Application of red light therapy during wakefulness improves sleep quality in people with cognitive decline, Guillain-Barré Syndrome, fibromyalgia and stroke. Interestingly, sleep duration decreased with full body red light therapy in elite athletes, while other parameters such as exercise recovery improved. When red light therapy is applied during sleep, there is an increased clearance of waste products from the brain and improved flow of cerebrospinal fluid, which are required for optimal brain health. So, red light therapy is beneficial when applied when either awake or sleeping, and the benefits relate more to improving sleep quality and physiology, rather than to increasing sleep duration. As already described, increased exposure to outdoor light is associated with reduced risk of major depression and greater happiness. Since outdoor light is a combination of visible light (including blue and red), infrared, and UV light, this contrasts with the light used in BLT, which includes only white visible light or blue monochromatic light. With so many studies showing a benefit to using red light therapy (especially infrared light), it is possible that the addition of red light in the treatment of SAD could be beneficial. Combining Bright and Red Light Therapy to Improve Seasonal Affective Disorder Red light therapy can easily be combined with BLT in the treatment of Seasonal Affective Disorder. Since the rising sun appears red when first coming up over the horizon, exposure to red light followed by exposure to BLT is recommended. This is a practice that I’ve been doing for several years, following decades of winter seasons in which I suffered from some degree of seasonal depression. Initially, my doctor recommended that I purchase a fluorescent light box, which I used successfully for a few years. After gaining knowledge of red light therapy, I combined the two and now use them in tandem. My recommended practice is as follows: Shortly after waking, use a red light therapy panel (that delivers both red and near infrared light) for 10 minutes, sitting comfortably 6 to 12 inches away. If you prefer, or if it’s uncomfortable to keep your eyes open in front of the red light panel, you can close them – light still penetrates through to the retinal ganglion cells. However, it is safe to open your eyes as long as your red light panel is low to moderate intensity. The 10 minutes spent in front of the red light panel provides a great opportunity to work on breathwork or mindfulness, which have positive effects on mood. After 10 minutes of red light therapy, use a light box that delivers white light (preferably using warm fluorescent bulbs, which have a lower blue light hazard ratio) for 20 minutes. It is possible to do normal activities while in front of the light box, so people usually set them up in an office (so that they can work on a computer or read) or on a kitchen island. I recommend setting it up in an office space and spending that 20 minutes engaged in an activity that generates a positive mood. For most people, this means avoiding reading the news, but you can do things like sending emails to friends or reading something uplifting. Taking time to be calm and to orient your attention in a positive direction uplifts mood. Avoid bright light, especially blue light, at night. Exposure to blue light (especially bright blue light) is disruptive to sleep, which is why it is not recommended to use electronic devices (like iPads or e-readers) that emit blue light at night. Keep household lighting dim in the evening and at night. Red light therapy may also be used at night, although you should position yourself farther from the panel so that the light is less intense. Red light panels can even be used as a source of evening/nighttime illumination. Red LED light bulbs may also be used as a source of illumination at night. Conclusion We often hear the recommendation by health experts these days to “view morning sun” as a way to optimize health, including mental health. While it is no doubt ideal to have exposure to natural light in the morning, for people that live in cold winter climates this can be very difficult. Under these circumstances, light devices – both bright and red light - can be used to mimic sunrise and sun exposure. Although the combination of bright and red/near infrared light has yet to be subject to intensive research, there is strong evidence that both exert a positive influence on mood. Since daylight consists of a combination of light wavelengths, including near infrared light, there is good reason to believe that these two may work in tandem as a powerful tool in the prevention and treatment of Seasonal Affective Disorder. For more information about Fringe light products, go to: https://fringeheals.com/shop-all-products/
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What is Earthing?
Earthing means connecting the body to the earth’s surface electric charge. Earthing is said to be a form of “electric nutrition” and a “universal regulating factor in Nature” because research has shown that it has a profound impact on human health (Menigoz et al., 2020). In fact, the simple act of regular contact with the earth has been shown to positively influence immune function, enhance muscle healing, improve bone health, reduce blood pressure, increase blood flow, enhance nervous system functioning, and improve sleep and mood. The earthing movement came out of Germany in the late 19th century and promoted sleeping on the ground outdoors and being barefoot outside as ways to achieve health (Just, 1903). In the 1920’s, Dr. G.S. White reported that sleeping on the ground, or connected to the earth such as by copper wire attached to grounded pipes, resulted in improved sleep (White, 1929). However, it wasn’t until the late 20th century that these ideas gained traction, when Clint Ober (Ober, 2000) and Sokal and Sokal (Sokal & Sokal, 2011) in Poland confirmed through research studies that there were many health benefits to being grounded to the earth. Ober, who worked with cable TV, realized this association through his experience with electrical systems, which require contact with the ground in order to be electrically stable. When these systems are connected to the negative charge on the earth’s surface they are said to be “grounded”. The term “grounding” is used synonymously with the term “earthing”. There are two ways to connect to the flow of electrons over the surface of earth: (1) directly, by putting the body in contact with natural conductive surfaces such as grass, soil, gravel, stone and sand; (2) putting the body in contact with grounded conductive mats, pads, body bands, or patches (usually while sitting or sleeping). The earth’s electron flow comes primarily from lightning strikes, solar radiation, and other atmospheric phenomena. These electron sources are continuous and give the earth a natural negative electric charge, since free electrons are negatively charged. (Menigoz et al., 2020). Until quite recently, it was the natural human state to be grounded virtually 24 hours a day. Humans walked barefoot and slept on the ground for most of our evolutionary history. Even when we adapted to wearing footwear and using bedding, it was made from animal skins that when moistened with ground moisture or sweat were able to conduct electrons from the ground to the body. Only recently have we shifted to wearing footwear with synthetic soles, living primarily on top of concrete. In this way, we might be said to be disconnected from our “electric roots” (Sinatra et al., 2017). The theory of “electron deficiency syndrome” states that as a consequence of the loss of an electric connection to the earth, that a natural source of electron flow to the body has been lost, which will have significant adverse physiological consequences (Oschman et al., 2015). Following this, it is possible that the loss of electric connection to the earth, a relatively recent phenomenon, might underlie (at least in part) the rise in global illness of the 21st and 22nd century (Menigoz et al., 2020). Humans As Bioelectrical Beings The idea that electron flow from the earth may play an important role in regulating human physiology is consistent with our understanding of humans as bioelectrical beings. Internal bioelectric signals regulate the function of the cardiovascular, nervous, immune and endocrine systems. The measurement of the body’s electrical character is called electrophysiology. The flow of electrons over the surface of the earth can be transferred into the human body through direct contact. Electrons have a negative charge, and in the body, like to occur in pairs. These electrons can act to neutralize free radicals, which have an unpaired electron that makes them unstable. Some free radicals are also known as reactive oxygen species. Free radicals are readily produced in the body and can do damage to surrounding cells and tissues. The free electron of a free radical can be “quenched” by an electron donor, stabilizing it in a pair. This is how antioxidants work – they act as electron donors to neutralize free radicals. In this way, the earth is seen as a giant antioxidant (Menigoz et al., 2020). Probing into this mechanism more deeply, it has been proposed that the electron flow provided by earthing may be able to break through the “inflammatory barricade” that can slow the healing response. This barricade develops in response to trauma or infection and serves to wall off damaged tissues and prevent bacteria, pathogens, or debris that result from an injury from travelling to (and harming) nearby tissues. However, the barricade also prevents treatments like antioxidants from accessing the site of injury, which can reduce the rate of healing. Because the barricade is made of the connective tissue collagen, which is a semi-conductor, electrons are able to cross through and perform their healing antioxidant action at the site of damage. In fact, all proteins act as semi-conductors which could have profound implications for the movement of electrons throughout the body. This may be particularly relevant for chronic inflammatory diseases (Sinatra et al., 2017). The effect of earthing on the electrical potential of the body has been demonstrated in research. Measurements of the body’s electrical induced fields in the left breast, abdomen, and left thigh were measured while both grounded and ungrounded, and it was found that the measured voltage in the grounded state was equalized with the Earth’s electrical potential. This voltage stayed constant despite the application of an electrical field. In contrast, when ungrounded, the application of an electrical field to the three body positions resulted in a large increase in electrical potential at the surface of the body, which is thought to disturb the electrical charges of molecules inside the body (Applewhite, 2005). As described by Nobel Prize winner Richard Feynman, when the electric potential of the body is the same as the Earth’s electric potential (which is what has been shown to occur during grounding), the body becomes an extension of the Earth’s electrical system in a phenomenon known as the “umbrella effect”, which results in the person being unaffected by electrical disturbances (Feynman et al., 1963). Earthing has also been shown to result in rapid changes in measures of body electrophysiology as measured by brain electroencephalograms (EEG’s) and muscle electromyograms (EMG’s) (Chevalier et al., 2006). This evidence clearly indicates that the concept of earthing affecting the electrical nature of the body is not merely theoretical. Effects of Earthing on the Body Immune System: The immune system regulates inflammation. Earthing has been shown to alter the inflammatory response to an injury, especially chronic infection. This is thought to be accomplished by passage of electrons through the inflammatory barricade previously described, which allows for healing following infection and injury. Inflammation has been shown through infrared imaging to decrease within 30 minutes of earthing, which is accompanied by metabolic changes that suggest tissue healing (Oschman et al, 2015). Earthing the human body has also been shown to speed up the immune response following vaccination. This has been demonstrated by measuring levels of immune markers in the blood following vaccination (Sokal & Sokal, 2011). Musculoskeletal System: Earthing helps muscles to recover from exercise. Three studies have shown that earthing is able to reduce delayed onset muscular soreness (DOMS) that occurs 24-72 hours after unusual or strenuous exercise. In the first study, 4 healthy men experienced a reduction in DOMS as well as pain and inflammation compared to a control group (Brown et al., 2010). In the second study, a larger group of 16 healthy men experienced similar effects (Brown et al., 2015). In the third study, subjects slept on an earthing sleep mat and compared to a control group, experienced positive effects such as a faster recovery, decreased inflammation, and less muscle damage (Müller et al., 2019). Earthing during cycling exercise has also been shown to significantly reduce the level of blood urea, which is an indicator of muscle and protein breakdown (Sokal et al., 2013). Based on these findings, it appears that earthing may be a simple and effective method to enhance recovery after exercise, which is important as very few interventions are known to help with DOMS. Bone health has also been shown to benefit from earthing. After a single night of sleeping grounded, subjects showed decreases in levels of the minerals calcium and phosphorus in both the blood and urine, which suggest a reduced rate of bone loss (Sokal & Sokal, 2011). Cardiovascular System: Earthing has been shown to improve blood flow in adults. Specifically, earthing has been found to increase the Zeta potential of red blood cells. The zeta potential is an indicator of the strength of the negative charge on the surface of red blood cells that helps to maintain the spacing of the blood cells while in the blood, which reduces the “viscosity” or thickness of the blood. When the zeta potential is higher, blood cells repel each other and there is less clumping and improved blood flow. In one study, the zeta potential increased by an average of 270% within two hours of earthing (Chevalier et al, 2013). The relationship of this effect to negative charge, and the speed of the effect, seems to clearly illustrate the electrical influence of earthing on the body. Earthing has also been shown to reduce blood pressure. In a study of 10 patients with hypertension, all subjects experienced a decrease in blood pressure with earthing. Blood pressure decreased when patients grounded themselves for at least 10 hours per day using a grounding mat. Systolic blood pressure decreased by an average of 14% (Elkin & Winter, 2018). Other cardiovascular related effects have been found with earthing. A placebo-controlled study found an increase in respiration rate, stabilization of blood oxygenation, and an increase in the pulse rate and perfusion index (a measure of blood flow) variability when grounded. These changes are thought to indicate the onset of a healing response that requires an increase in oxygen consumption (Chevalier, 2010). Autonomic Nervous System: Earthing affects the function of the autonomic nervous system (ANS) in both infants and adults. The ANS is responsible for regulating body processes such as heart rate, blood pressure, respiration and digestion. When earthing patches were placed on the skin of premature babies, within minutes increases in heart rate variability (HRV) were observed, which indicate better functioning of the ANS. This may help to reduce the risk of necrotizing enterocolitis, which is severe illness that affects about 10% of premature infants and can cause death (Passi et al., 2017). In adults, earthing has been found to cause a shift from an overactive expression of the sympathetic nervous system (“fight or flight”) to a parasympathetic (“rest and digest”) state that regulates heart rate, respiration, digestion, and other functions (Chevalier, 2010). Earthing also exerts a normalizing effects on levels of the stress-related hormone cortisol (Ghaly & Teplitz, 2004). In this way, earthing has the effect of reducing stress. Skin: Earthing has been found to increase blood flow to the skin. Following earthing, there was a rapid increase in blood flow to the face in a placebo-controlled study in which the control group was given a “sham” earthing experience (Chevalier, 2014). This might explain the results of a survey that found that women reported having better facial complexions after earthing (The Earthing Institute). Increased blood flow to the face, neck and torso has also been shown following earthing (Chevalier, 2015). The effects of earthing on the skin have also been studied in the context of wound healing. A case study of an 84 year old woman with an eight-month old open wound near her ankle responded dramatically to two weeks of using an earthing patch after several unsuccessful treatments at a specialized wound center (Sinatra et al., 2017). This is consistent with animal research that shows that electric currents increase energy production and protein synthesis in rat skin (Cheng et al., 1982). Sleep: Many people report better sleep with earthing. The first report of improved sleep with grounding came in the 1920’s from Dr. G.S. White (White, 1929). More recently, in a study of 12 participants, 11 subjects reported that they fell asleep faster and all subjects reported fewer nighttime awakenings after 8 weeks. Subjects also showed normalization in their 24-hour profile of cortisol secretion (Ghaly & Teplitz, 2004). Similarly, in a controlled, blinded study of 60 subjects who reported disturbed sleep and chronic muscle and joint pain, the group who slept on the grounded sleep mats reported a wide variety of benefits, including improved sleep and sleep apnea after one month (Ober et al., 2010). Mood: Earthing has been shown to improve mood. In a double-blind, placebo-controlled study of 40 adult men and women, those who spent an hour sitting comfortably in a recliner on a grounded mat, with their head on a grounded pillow, and with grounding patches on their palms and soles showed significantly improved mood compared to the control group, who used the same products that were not grounded. Specifically, participants reported a more pleasant mood, feeling less tired and more relaxed, and feeling more positive (Chevalier, 2015). Clinical Recommendations Earthing represents an incredibly safe, inexpensive, and effective intervention that can easily be integrated into one’ life. There are three ways that health care providers can recommend earthing to their patients. These are: 1. Earthing outdoors. Sessions of 30-40 minutes daily have been shown to be effective (Sinatra 18). This is also the most inexpensive method of earthing. People can go barefoot outdoors or can buy outdoor conductive footwear. Unfortunately, time and weather may be limiting factors. Also note that in order for electron transfer to occur, one must be on a natural conductive surface, such as soil, sand, gravel, grass or stone. 2. Earthing products. There are a number of grounding products that are available commercially. These include sleep mats, blankets, bands, patches, chairs, and mats. These products are connected via an electrical cord to a grounded outlet, or less commonly, to a grounding pole placed in the earth. Prices vary but are quite reasonable. 3. Earthing in clinic. Health care practitioners can provide treatments to patients while lying on an earthing mat, or can provide in-clinic earthing sessions where patients use grounding products like chairs, mats, and patches. Conclusion Our modern lifestyles provide us with many benefits, but they also have served to disconnect us from the earth. It is becoming increasingly clear that this may have adverse effects on our health, and conversely, that health can be improved by reconnecting with the “electric nutrition” of the earth in some way. While earthing outdoors is a free and easy way to get grounded, there are many accessible products available that can facilitate this connection. Given the ease and safety of this intervention, it is recommended that everyone incorporate earthing into their routine of health maintenance and disease prevention. For more information about Fringe light products, go to: https://fringeheals.com/shop-all-products/ References Applewhite R. (2005). The effectiveness of a conductive patch and a conductive bed pad in reducing induced human body voltage via the application of earth ground.” European Biology and Bioelectromagnetics; 1: 23–40. Brown, D., Chevalier, G., & Hill, M. (2010). Pilot study on the effect of grounding on delayed-onset muscle soreness. Journal of alternative and complementary medicine (New York, N.Y.), 16(3), 265–273. https://doi.org/10.1089/acm.2009.0399 Brown, R., Chevalier, G., & Hill, M. (2015). Grounding after moderate eccentric contractions reduces muscle damage. Open access journal of sports medicine, 6, 305–317. https://doi.org/10.2147/OAJSM.S87970 Cheng, N., Van Hoof, H., Bockx, E., Hoogmartens, M. J., Mulier, J. C., De Dijcker, F. J., Sansen, W. M., & De Loecker, W. (1982). The effects of electric currents on ATP generation, protein synthesis, and membrane transport of rat skin. Clinical orthopaedics and related research, (171), 264–272. Chevalier G. (2010). Changes in pulse rate, respiratory rate, blood oxygenation, perfusion index, skin conductance, and their variability induced during and after grounding human subjects for 40 minutes. Journal of alternative and complementary medicine (New York, N.Y.), 16(1), 81–87. Chevalier G. (2015). The effect of grounding the human body on mood. Psychological reports, 116(2), 534–542. https://doi.org/10.2466/06.PR0.116k21w5 Chevalier, G. (2014). Grounding the human body improves facial blood flow regulation: Results of a randomized placebo controlled pilot study. Journal of Cosmetic, Dermatological Sciences and Applications, 4, 293-308. Chevalier, G. (2015) One-hour contact with the Earth’s surface (grounding) improves inflammation and blood flow – A randomized, double-blind pilot study. Health, 7, 1022-1059. Chevalier, G., Mori, K., & Oschman, J.L. (2006). The effect of Earthing (grounding) on human physiology, European Biology and Bioelectromagnetics, 2(1), 600-621. Chevalier, G., Sinatra, S. T., Oschman, J. L., & Delany, R. M. (2013). Earthing (grounding) the human body reduces blood viscosity-a major factor in cardiovascular disease. Journal of alternative and complementary medicine (New York, N.Y.), 19(2), 102–110. https://doi.org/10.1089/acm.2011.0820 Elkin, H. K., & Winter, A. (2018). Grounding Patients With Hypertension Improves Blood Pressure: A Case History Series Study. Alternative therapies in health and medicine, 24(6), 46–50. Feynman, R., Leighton, R., & Sands, M. (1963). The Feynman Lectures on Physics, vol.II, Addison-Wesley, Boston, Mass, USA. Ghaly, M., & Teplitz, D. (2004). The biologic effects of grounding the human body during sleep as measured by cortisol levels and subjective reporting of sleep, pain, and stress. Journal of alternative and complementary medicine (New York, N.Y.), 10(5), 767–776. https://doi.org/10.1089/acm.2004.10.767 https://earthinginstitute.net/rapid-benefits-an-earthing-1-hour-time-trial/ Just, A. Return to Nature: The True Natural Method of Healing and Living and The True Salvation of the Soul. New York, NY: B. Lust; 1903. Menigoz, W., Latz, T. T., Ely, R. A., Kamei, C., Melvin, G., & Sinatra, D. (2020). Integrative and lifestyle medicine strategies should include Earthing (grounding): Review of research evidence and clinical observations. Explore (New York, N.Y.), 16(3), 152–160. https://doi.org/10.1016/j.explore.2019.10.005 Müller, E., Pröller, P., Ferreira-Briza, F., Aglas, L., & Stöggl, T. (2019). Effectiveness of Grounded Sleeping on Recovery After Intensive Eccentric Muscle Loading. Frontiers in physiology, 10, 35. https://doi.org/10.3389/fphys.2019.00035 Ober C, Sinatra ST, Zucker M. Earthing: The Most Important Health Discovery Ever? Laguna Beach, Calif, USA: Basic Health Publications; 2010. Ober, C. Grounding the human body to neutralize bioelectrical stress from static electricity and EMF’s. ESD Journal Web site: http://www.esdjournal.com/articles/cober/ground.htm. Accessed June 27th, 2021. Oschman, J. L., Chevalier, G., & Brown, R. (2015). The effects of grounding (earthing) on inflammation, the immune response, wound healing, and prevention and treatment of chronic inflammatory and autoimmune diseases. Journal of Inflammation Research, 8, 83–96. https://doi.org/10.2147/JIR.S69656 Passi, R., Doheny, K. K., Gordin, Y., Hinssen, H., & Palmer, C. (2017). Electrical Grounding Improves Vagal Tone in Preterm Infants. Neonatology, 112(2), 187–192. https://doi.org/10.1159/000475744 Sinatra, S. T., Oschman, J. L., Chevalier, G., & Sinatra, D. (2017). Electric Nutrition: The Surprising Health and Healing Benefits of Biological Grounding (Earthing). Alternative therapies in health and Medicine, 23(5), 8–16. Sokal, K., & Sokal, P. (2011). Earthing the human body influences physiologic processes. Journal of alternative and complementary medicine (New York, N.Y.), 17(4), 301–308. https://doi.org/10.1089/acm.2010.0687 Sokal, K., & Sokal, P. (2011). Earthing the human body influences physiologic processes. Journal of alternative and complementary medicine (New York, N.Y.), 17(4), 301–308. https://doi.org/10.1089/acm.2010.0687 Sokal, P., Jastrzębski, Z., Jaskulska, E., Sokal, K., Jastrzębska, M., Radzimiński, L., Dargiewicz, R., & Zieliński, P. (2013). Differences in Blood Urea and Creatinine Concentrations in Earthed and Unearthed Subjects during Cycling Exercise and Recovery. Evidence-based complementary and alternative medicine : eCAM, 2013, 382643. https://doi.org/10.1155/2013/382643 White, G. The Finer Forces of Nature in Diagnosis and Therapy. Albuquerque, NM: Sun Publishing; 1929.
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